Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00607 |
Cytosine deaminase Protein, E. coli, Recombinant (His & SUMO)
CD,Cytosine deaminase,CDase,CDA,codA,C... |
E. coli | E. coli |
Cytosine deaminase Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.5 kDa and the accession number is P25524. | |||
TMPH-02908 |
AICDA Protein, Mouse, Recombinant (His & Myc)
Single-stranded DNA cytosine deaminase,Cyt... |
Mouse | E. coli |
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. | |||
TMPH-01235 |
APOBEC3A Protein, Human, Recombinant (His & SUMO)
A3A,APOBEC3A,DNA dC->dU-editing enzyme APOBEC-3A,Phorbolin-1 |
Human | E. coli |
DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a rol... |